基因名：
KEAP1
产品别名：
INrf2； KLHL19； KEAP1； kelch like ECH associated protein 1； kelch like ECH associated protein 1； kelch-like ECH-associated protein 1； KEAP1 delta C； cytosolic inhibitor of Nrf2； kelch-like family member 19； kelch-like protein 19； Kelch样ECH关联蛋白1(KEAP1)； 胞质接头蛋白Keap1；
背景信息：
This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene. [provided by RefSeq, Jul 2008].
