基因名：
KMT2B
产品别名：
CXXC10； DYT28； HRX2； MLL1B； MLL2； MLL4； MRD68； TRX2； WBP-7； WBP7； KMT2B； lysine methyltransferase 2B； lysine methyltransferase 2B； histone-lysine N-methyltransferase 2B； WW domain binding protein 7； histone-lysine N-methyltransferase MLL4； lysine (K)-specific methyltransferase 2B； mixed lineage leukemia gene homolog 2； myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) 4； myeloid/lymphoid or mixed-lineage leukemia protein 4； trithorax homologue 2； 组蛋白赖氨酸N-甲基转移酶2B；
背景信息：
This gene encodes a protein which contains multiple domains including a CXXC zinc finger, three PHD zinc fingers, two FY-rich domains, and a SET (suppressor of variegation, enhancer of zeste, and trithorax) domain. The SET domain is a conserved C-terminal domain that characterizes proteins of the MLL (mixed-lineage leukemia) family. This gene is ubiquitously expressed in adult tissues. It is also amplified in solid tumor cell lines, and may be involved in human cancer. Two alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene, however, the full length nature of the shorter transcript is not known. [provided by RefSeq, Jul 2008]
