基因名:
MORF4L2
产品别名:
MORFL2; MRGX; MORF4L2; mortality factor 4 like 2; mortality factor 4 like 2; mortality factor 4-like protein 2; MORF-related gene X protein; MSL3-2 protein; protein MSL3-2; transcription factor-like protein MRGX; 死亡因子4样蛋白2;
背景信息:
Mortality Factor 4-Like Protein 2 (MORF4L2) is a member of the mortality factor (MORF) family. MORF4L2 localizes in the nucleus, possessing a protein kinase C phosphorylation site and a tyrosine phosphorylation site. MORF4L2 interacts with the Rb tumor suppressor and it has histone deacetylase activity which can either repress or promote the activity of the B-Myb promoter depending on the tissue. In addition, MORF4L2 is involved in cell growth, regulation, and senescence.