基因名：
MACROH2A1
产品别名：
H2A.y； H2A/y； H2AF12M； H2AFY； MACROH2A1.1； mH2A1； macroH2A1.2； MACROH2A1； macroH2A.1 histone； macroH2A.1 histone； core histone macro-H2A.1； H2A histone family member Y； histone H2A.y； histone macroH2A1； histone macroH2A1.1； histone macroH2A1.2； medulloblastoma antigen MU-MB-50.205； 异型组蛋白H2A.1；
背景信息：
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and participates in stable X chromosome inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
