基因名：
APBA3
产品别名：
MGC:15815； X11L2； mint3； APBA3； amyloid beta precursor protein binding family A member 3； amyloid beta precursor protein binding family A member 3； amyloid-beta A4 precursor protein-binding family A member 3； X11-like 2 protein； adapter protein X11gamma； amyloid beta (A4) precursor protein-binding, family A, member 3 (X11-like 2)； mint-3； neuron-specific X11L2 protein； neuronal munc18-1-interacting protein 3； phosphotyrosine-binding/-interacting domain (PTB)-bearing protein； β淀粉样前体蛋白结合蛋白3； 淀粉样蛋白β前体蛋白结合蛋白A3(APBA3)；
背景信息：
Amyloid β A4 Precursor Protein-Binding Family A Member 3 (APBA3) is an adapter protein that belongs to the X11 family. APBA3 contains 2 PDZ (DHR) domains and 1 PID domain and interacts with the Alzheimer's disease amyloid precursor protein.. APBA3 is believed to be involved in signal transduction processes. Unlike X11-α and -β which are generally neuronal proteins, APBA3 is widely expressed in all tissues examined with lower levels in brain and testis. It binds to the cytoplasmic domain of amyloid protein (APP) in vivo and may modulate processing of the β-amyloid precursor protein (APP) and hence formation of β-APP.
