基因名：
TRIP10
产品别名：
CIP4； HSTP； STOT； STP； TRIP-10； TRIP10； thyroid hormone receptor interactor 10； thyroid hormone receptor interactor 10； cdc42-interacting protein 4； TR-interacting protein 10； protein Felic； salt tolerant protein； salt tolerator； thyroid receptor-interacting protein 10； 细胞分化周期CDC424；
背景信息：
Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling (By similarity). Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention of FASLG/FASL.
