基因名:
LRRFIP2
产品别名:
HUFI-2; LRRFIP2; LRR binding FLII interacting protein 2; LRR binding FLII interacting protein 2; leucine-rich repeat flightless-interacting protein 2; LRR FLII-interacting protein 2; leucine rich repeat (in FLII) interacting protein 2; LRRFIP2蛋白;
背景信息:
LRRFIP2 is a 721 amino acid protein that belongs to the LRRFIP family. Ubiquitously expressed, LRRFIP2 acts as an activator of the Wnt signaling pathway and as a positive regulator of NFⅹB activity. LRRFIP2 may be involved in regulating cytokine production in macrophages, suggesting a functional role in the TLR4-mediated inflammatory response. Three isoforms of LRRFIP2 exists due to alternative splicing events.