基因名：
OSMR
产品别名：
IL-31R-beta； IL-31RB； OSMRB； OSMRbeta； PLCA1； OSMR； oncostatin M receptor； oncostatin M receptor； oncostatin-M-specific receptor subunit beta； IL-31 receptor subunit beta； IL-31R subunit beta； interleukin-31 receptor subunit beta； oncostatin-M specific receptor beta subunit； 抑瘤素M受体； 抑瘤素M受体(OSMR)；
背景信息：
Oncostatin-M-Specific Receptor Subunit β (OSMRβ) is a 150 - 180 kDa member of the IL-6 receptor family. OSMRβ associates with gp130 to form the type II OSM receptor, the receptor is responsive to OSM. Gp130 subunit is shared by other IL-6 family cytokine receptors, and OSMRβ associates with gp130-like receptor (GPL) to form a receptor complex responsive to IL-31. The human OSMRβ cDNA encodes a 979 amino acid (aa) precursor, the precursor includes a 27 aa signal sequence, a 712 aa extracellular domain (ECD), a 22 aatransmembrane segment, and a 218 aa cytoplasmic domain. The ECD contains one partial and one complete hematopoietin domain, an Ig-like domain, and three Fibronectin type-III domains.
