基因名:
ATG12
产品别名:
APG12; APG12L; FBR93; HAPG12; ATG12; autophagy related 12; autophagy related 12; ubiquitin-like protein ATG12; APG12 autophagy 12-like; ATG12 autophagy related 12 homolog; Apg12 (autophagy, yeast) homolog; 自噬相关蛋白12;
背景信息:
Autophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. ATG12 is the human homolog of a yeast protein involved in autophagy (Mizushima et al., 1998[PubMed 9852036]).[supplied by OMIM].