基因名:
F2RL3
产品别名:
PAR4; F2RL3; F2R like thrombin or trypsin receptor 3; F2R like thrombin or trypsin receptor 3; proteinase-activated receptor 4; F2R like thrombin/trypsin receptor 3; PAR-4; coagulation factor II (thrombin) receptor-like 3; protease-activated receptor-4; thrombin receptor-like 3; 蛋白酶活化受体4;
背景信息:
Coagulation factor II (thrombin) receptor-like 3 (F2RL3) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL3 is also a member of the protease-activated receptor family. F2RL3 is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. F2RL3 is activated by thrombin and trypsin. [provided by RefSeq, Jul 2008]