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重组B-细胞淋巴瘤因子10(Bcl10)蛋白
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。

重组磷酸化BCL10蛋白
Recombinant BCL10
基因名:

BCL10


产品别名:

CARMEN; CIPER; CLAP; IMD37; c-E10; mE10; BCL10; BCL10 immune signaling adaptor; BCL10 immune signaling adaptor; B-cell lymphoma/leukemia 10; B cell CLL/lymphoma 10; CARD containing molecule enhancing NF-kB; CARD-containing apoptotic signaling protein; CARD-containing molecule enhancing NF-kappa-B; CARD-containing proapoptotic protein; CED-3/ICH-1 prodomain homologous E10-like regulator; cCARMEN; caspase-recruiting domain-containing protein; cellular homolog of vCARMEN; cellular-E10; hCLAP; mammalian CARD-containing adapter molecule E10; B-细胞淋巴瘤因子10(Bcl10); 磷酸化BCL10;


背景信息:
Bcl10/CIPER/CLAP/mE10 is expressed in many human and murine tissues. It contains a CARD (caspase recruiting domain) domain and is involved in activation of caspase9 to induce apoptosis. It is a cellular homolog of equine herpesvirus 2 E-10. It is known to induce activation of JNK, p38 and NF kappaB. Mutations in Bcl10 are observed in many B and T cell lymphomas implicating its role in pathogenesis of human cancer.
 
 
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