重组肿瘤坏死因子受体超家族成员10C(TNFRSF10C)蛋白

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重组肿瘤坏死因子配体超家族成员10C蛋白
Recombinant TNFRSF10C

基因名：

TNFRSF10C

产品别名：

CD263； DCR1； DCR1-TNFR； LIT； TRAIL-R3； TRAILR3； TRID； TNFRSF10C； TNF receptor superfamily member 10c； TNF receptor superfamily member 10c； tumor necrosis factor receptor superfamily member 10C； TNF-related apoptosis-inducing ligand receptor 3； antagonist decoy receptor for TRAIL/Apo-2L； cytotoxic TRAIL receptor-3； decoy TRAIL receptor without death domain； decoy receptor 1； lymphocyte inhibitor of TRAIL； tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain；肿瘤坏死因子受体超家族成员10C(TNFRSF10C)；肿瘤坏死因子配体超家族成员10C；

背景信息：

Tumor Necrosis Factor Receptor Superfamily Member 10C (TNFRSF10C) is a glycosyl-phosphatidylinositol-linked membrane protein which binds TRAIL with high affinity. TNFRSF10C has the TRAIL-binding extracellular cysteine-rich domains, lacks the intracellular signaling domain. As a result, binding of TRAIL to TRAIL R3 doesn’t transduce an apoptosis signal. The expression of TRAIL R3 gene has been shown to protect cells bearing TRAIL R1 and/or TRAIL R2 from TRAIL-induced apoptosis.