基因名：
RIPK1
产品别名：
AIEFL； IMD57； RIP； RIP-1； RIP1； RIPK1； receptor interacting serine/threonine kinase 1； receptor interacting serine/threonine kinase 1； receptor-interacting serine/threonine-protein kinase 1； cell death protein RIP； receptor (TNFRSF)-interacting serine-threonine kinase 1； receptor-interacting protein 1； receptor-interacting protein kinase 1； serine/threonine-protein kinase RIP； 丝氨酸苏氨酸激酶1受体； 受体相互作用丝氨酸苏氨酸激酶1(RIPK1)；
背景信息：
Can activate specifically hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. Can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. Serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDK1 to switch off endocytosis, One of its substrates would be EPN1/Epsin.
