基因名:
NUMB
产品别名:
C14orf41; S171; c14_5527; NUMB; NUMB endocytic adaptor protein; NUMB endocytic adaptor protein; protein numb homolog; h-Numb; numb homolog; Numb同源物(NUMB); 磷酸化膜相关蛋白Numb; 膜相关蛋白Numb;
背景信息:
The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].