基因名:
LGR5
产品别名:
FEX; GPR49; GPR67; GRP49; HG38; LGR5; leucine rich repeat containing G protein-coupled receptor 5; leucine rich repeat containing G protein-coupled receptor 5; leucine-rich repeat-containing G-protein coupled receptor 5; G-protein coupled receptor 49; G-protein coupled receptor 67; G-protein coupled receptor HG38; orphan G protein-coupled receptor HG38; G蛋白偶联受体49; 含亮氨酸丰富重复G蛋白偶联受体5(LGR5);
背景信息:
The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]