基因名：
PPFIA1
产品别名：
LIP.1； LIP1； LIPRIN； PPFIA1； PTPRF interacting protein alpha 1； PTPRF interacting protein alpha 1； liprin-alpha-1； LAR-interacting protein 1； LIP-1； Liprin-alpha1； protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1； protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1； 蛋白酪氨酸激酶F相互作用蛋白1(PPFIA1)； 酪氨酸磷酸酶受体Liprinα1；
背景信息：
The protein encoded by this gene is a member of the LARprotein-tyrosine phosphatase-interacting protein (liprin) family.Liprins interact with members of LAR family of transmembraneprotein tyrosine phosphatases, which are known to be important foraxon guidance and mammary gland development. This protein binds tothe intracellular membrane-distal phosphatase domain of tyrosinephosphatase LAR, and appears to localize LAR to cell focaladhesions. This interaction may regulate the disassembly of focaladhesion and thus help orchestrate cell-matrix interactions.Alternatively spliced transcript variants encoding distinctisoforms have been described. [provided by RefSeq, Jul 2008].
