基因名：
SEMA7A
产品别名：
CD108； CDw108； H-SEMA-K1； H-Sema-L； JMH； PFIC11； SEMAK1； SEMAL； SEMA7A； semaphorin 7A (John Milton Hagen blood group)； semaphorin 7A (John Milton Hagen blood group)； semaphorin-7A； JMH blood group antigen； John Milton Hagen blood group H-Sema K1； john-Milton-Hargen human blood group Ag； sema K1； sema L； sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A (JMH blood group)； sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, 7A； semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)； semaphorin-K1； semaphorin-L； 信号素7A(SEMA7A)； 轴突生长因子CD108；
背景信息：
Semaphorin 7a is required for central and peripheral axon growth and is required for proper axon tract formation during embryonic development. Semaphorin 7a is also involved in modulating immune function. Semaphorin 7a expression is highest in the brain and increases in late embryonic and postnatal stages. The Semaphorins constitute a large family of secreted and membrane-tethered cell signaling molecules. They have functions in neural development, immunology, cardiac growth, vascular development, lung morphogenesis and axial bone patterning. Semaphorins are defined by the presence of a conserved Sema domain at the N-terminus. These proteins can be classified into eight classes depending on their structure and species origin. Classes 3 through 7 are found in vertebrates; class 3 are secreted, class 7 are GPI-anchored, and class 4 through 6 are transmembrane proteins.
