基因名:
IRS4
产品别名:
CHNG9; IRS-4; PY160; IRS4; insulin receptor substrate 4; insulin receptor substrate 4; insulin receptor substrate 4; 160 kDa phosphotyrosine protein; phosphoprotein of 160 kDa; pp160; 胰岛素受体底物-4; 胰岛素受体底物4(IRS4);
背景信息:
IRS4 (Insulin receptor substrate 4) is a cytoplasmic protein that contains many potential tyrosine and serine/threonine phosphorylation sites. Tyrosine-phosphorylated IRS4 protein has been shown to associate with cytoplasmic signaling molecules that contain SH2 domains. The IRS4 protein is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation.