基因名：
CDC7
产品别名：
CDC7L1； HsCDC7； Hsk1； huCDC7； CDC7； cell division cycle 7； cell division cycle 7； cell division cycle 7-related protein kinase； CDC7 (cell division cycle 7, S. cerevisiae, homolog)-like 1； CDC7-related kinase； cell division cycle 7 homolog； cell division cycle 7-like protein 1； epididymis secretory sperm binding protein； 细胞分裂周期因子7(CDC7)； 细胞分裂周期蛋白7；
背景信息：
DNA replication in eukaryotic cells is dependent on the phosphorylation of the pre-replicative complex (preRC) at the origin of replication. Two complexes of proteins mediate this event, the cyclin dependent kinase (CDK) complex, and the Cdc7 kinase-ASK complex. The activity of Cdc7 kinase oscillates during cell cycle. The major targets of Cdc7 kinase are proteins that belong to the MCM complex (mini chromosome maintenance proteins). Cdc7 kinase was also found to be important in meiosis, checkpoint responses, maintenance of chromosome structure, and repair.
