基因名：
RAB7A
产品别名：
CMT2B； PRO2706； RAB7； RAB7A； RAB7A, member RAS oncogene family； RAB7A, member RAS oncogene family； ras-related protein Rab-7a； RAB7, member RAS oncogene family； Ras-associated protein RAB7； RAS癌基因家族成员RAB7A(RAB7A)； RAS癌基因相关蛋白RAB7；
背景信息：
RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways. This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This encoded protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori. Mutations at highly conserved amino acid residues in this gene have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies. [provided by RefSeq, Jul 2008]
