基因名：
BTG2
产品别名：
APRO1； PC3； TIS21； BTG2； BTG anti-proliferation factor 2； BTG anti-proliferation factor 2； protein BTG2； B-cell translocation gene 2； BTG family member 2； NGF-inducible anti-proliferative protein PC3； nerve growth factor-inducible anti-proliferative； pheochromacytoma cell-3； B细胞迁移基因2；
背景信息：
BTG2 is a member of the BTG/Tob family. This family has structurally related proteins that appear to have antiproliferative properties. BTG2 is involved in the regulation of the G1/S transition of the cell cycle. It modulates transcription regulation mediated by ESR1(referenced from Entrez Gene). BTG2 expression is induced in vivo during neurogenesis, and the gene is transiently expressed in vitro in rat pheochromocytoma PC12 cells after induction of neuronal differentiation by addition of nerve growth factor (NGF); suggesting that BTG2 is functionally significant during the neuronal differentiation process (PMID: 12360398).
