基因名:
WARS1
产品别名:
GAMMA-2; HMN9; IFI53; IFP53; WARS; WARS1; tryptophanyl-tRNA synthetase 1; tryptophanyl-tRNA synthetase 1; tryptophan--tRNA ligase, cytoplasmic; epididymis secretory sperm binding protein; hWRS; interferon-induced protein 53; trpRS; tryptophan tRNA ligase 1, cytoplasmic; 色氨酰tRNA合成酶(WARS);
背景信息:
There exists two types of tryptophanyl tRNA synthetases, the cytoplasmic form called WARS, the mitochondrial form called WARS2. WARS catalyzes the aminoacylation of tRNA (trp) with tryptophan and is induced by interferon. WARS regulates ERK, Akt, eNOS activation pathway, which are related with angiogenesis, cytoskelatal reorganization and shear stess-reponsive gene expression.