基因名:
USP1
产品别名:
UBP; USP1; ubiquitin specific peptidase 1; ubiquitin specific peptidase 1; ubiquitin carboxyl-terminal hydrolase 1; Ubiquitinyl hydrolase 1, Ubiquitin carboxyl-terminal hydrolase 1, ubiquitin thiolesterase 1; deubiquitinating enzyme 1; hUBP; ubiquitin specific processing protease 1; ubiquitin specific protease 1; ubiquitin thioesterase 1; ubiquitin thiolesterase 1; 泛素特异性肽酶1(USP1); 泛素特异性蛋白酶1;
背景信息:
This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. The protein specifically deubiquitinates a protein in the Fanconi anemia (FA) DNA repair pathway. Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008]