基因名:
UGCG
产品别名:
GCS; GLCT1; UGCG; UDP-glucose ceramide glucosyltransferase; UDP-glucose ceramide glucosyltransferase; ceramide glucosyltransferase; UDP-glucose:N-acylsphingosine D-glucosyltransferase; glucosylceramide synthase; glycosylceramide synthase; UDP葡萄糖神经酰胺葡萄糖基转移酶(UGCG); 葡萄糖神经酰胺合成酶; 谷氨酸半胱氨酸γ合成酶;
背景信息:
GCS (glucosylceramide synthase ) may serve as a 'flippase' as well as a glucosyltransferase that transfers glucose to ceramide. Able to use UDP-galactose to synthesize galactosylceramide with 10% of efficiency with which it utilizes UDP-glucose. [Catalytic activity] UDP-glucose + N-acylsphingosine = UDP + D-glucosyl-N-acylsphingosine. Lipid metabolism; sphingolipid metabolism. [Subcellular location] Endoplasmic reticulum membrane; Multi-pass membrane protein. Belongs to the glycosyltransferase 2 family.