基因名：
UBE2V2
产品别名：
DDVIT1； DDVit-1； EDAF-1； EDPF-1； EDPF1； MMS2； UEV-2； UEV2； UBE2V2； ubiquitin conjugating enzyme E2 V2； ubiquitin conjugating enzyme E2 V2； ubiquitin-conjugating enzyme E2 variant 2； 1 alpha,25-dihydroxyvitamin D3-inducible； DDVit 1； MMS2 homolog； enterocyte differentiation promoting factor； enterocyte differentiation-associated factor 1； enterocyte differentiation-associated factor EDAF-1； enterocyte differentiation-promoting factor 1； methyl methanesulfonate sensitive 2, S. cerevisiae, homolog of； vitamin D3-inducible protein； 肠细胞分化相关因子1；
背景信息：
Ubiquitin-Conjugating Enzyme E2 Variant 2 (UBE2V2) is an enzyme that belongs to the ubiquitin-conjugating enzyme family. UBE2V2 can be detected in the placenta, colon, liver, and skin. It forms a heterodimer with UBE2N. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains and which leads to protein degradation by the proteasome. UBE2V2 mediates transcriptional activation of target genes. It plays a role in the control of progress through the cell cycle and differentiation. It also plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.
