重组泛素结合酶E2C结合蛋白E2D1(UBE2D1)

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重组泛素蛋白连接酶D1
Recombinant UBE2D1

基因名：

UBE2D1

产品别名：

E2(17)KB1； SFT； UBC4/5； UBCH5； UBCH5A； UBE2D1； ubiquitin conjugating enzyme E2 D1； ubiquitin conjugating enzyme E2 D1； ubiquitin-conjugating enzyme E2 D1； (E3-independent) E2 ubiquitin-conjugating enzyme D1； E2 ubiquitin-conjugating enzyme D1； UBC4/5 homolog； stimulator of Fe transport； ubiquitin carrier protein D1； ubiquitin conjugating enzyme E2D 1； ubiquitin-conjugating enzyme E2(17)KB 1； ubiquitin-conjugating enzyme E2-17 kDa 1； ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)； ubiquitin-protein ligase D1；泛素结合酶E2C结合蛋白E2D1(UBE2D1)；泛素蛋白连接酶D1；

背景信息：

Ubiquitin-conjugating enzyme E2 D1（UBE2D1）belongs to the ubiquitin-conjugating enzyme family. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases.