基因名:
TTK
产品别名:
CT96; ESK; MPH1; MPS1; MPS1L1; PYT; TTK; TTK protein kinase; TTK protein kinase; dual specificity protein kinase TTK; cancer/testis antigen 96; monopolar spindle 1 kinase; monopolar spindle 1-like 1; phosphotyrosine picked threonine kinase; phosphotyrosine picked threonine-protein kinase; TTK蛋白激酶(TTK); 单极纺锤体蛋白激酶1;
背景信息:
Mps1 (TTK) is a tyrosine and serine/threonine dual-specificity kinase required for centrosome duplication and the spindle checkpoint and has recently been shown to have a role in centrosome duplication. Alterations to Mps1 have been associated with cell transformation and chromosome instability in different tumor models. It is present in rapidly proliferating cell lines.