基因名:
TRAF2
产品别名:
MGC:45012; RNF117; TRAP; TRAP3; TRAF2; TNF receptor associated factor 2; TNF receptor associated factor 2; TNF receptor-associated factor 2; E3 ubiquitin-protein ligase TRAF2; RING-type E3 ubiquitin transferase TRAF2; tumor necrosis factor type 2 receptor associated protein 3; TNF受体关联因子2(TRAF2); 肿瘤坏死因子受体相关因子2;
背景信息:
The induction of the various cellular responses mediated by tumor necrosis factor is initiated by its interaction with the TNFR1 and TNFR2 cell surface receptors. TRAF2 interacts with the cytoplasmic domain of TNFR2. TRAF2 is a common signal transducer for TNFR2 and CD40 that mediates activation of NF kappa B.