基因名:
TPH1
产品别名:
TPRH; TRPH; TPH1; tryptophan hydroxylase 1; tryptophan hydroxylase 1; tryptophan 5-hydroxylase 1; L-tryptophan hydroxylase; indoleacetic acid-5-hydroxylase; tryptophan 5-monooxygenase 1; tryptophan hydroxylase (tryptophan 5-monooxygenase); 磷酸化色氨酸羟化酶; 色氨酸羟化酶; 色氨酸羟化酶1(TPH1);
背景信息:
This gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others.[provided by RefSeq, Apr 2009].