基因名：
TP53BP1
产品别名：
53BP1； TDRD30； p202； p53BP1； TP53BP1； tumor protein p53 binding protein 1； tumor protein p53 binding protein 1； TP53-binding protein 1； p53-binding protein 1； tumor protein 53-binding protein, 1； tumor suppressor p53-binding protein 1； p53结合蛋白1； 磷酸化p53结合蛋白1； 肿瘤蛋白p53结合蛋白1(TP53BP1)；
背景信息：
p53 binding protein 1 (53BP1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, it is phosphorylated and relocalizes to the presumptive sites of damage, p53 binding protein 1 (53BP1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, it is phosphorylated and relocalizes to the presumptive sites of damage, specifically, double strand breaks. This also suggests a role in DNA repair, maintaining genomic stability.
