基因名:
SEC62
产品别名:
Dtrp1; HTP1; TLOC1; TP-1; SEC62; SEC62 homolog, preprotein translocation factor; SEC62 homolog, preprotein translocation factor; translocation protein SEC62; SEC62 preprotein translocation factor; hTP-1; membrane protein SEC62, S.cerevisiae, homolog of; translocation protein 1; 转运蛋白SEC62;
背景信息:
The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC63 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER. [provided by RefSeq, Jul 2008]