基因名:
TGM3
产品别名:
TGE; UHS2; TGM3; transglutaminase 3; transglutaminase 3; protein-glutamine gamma-glutamyltransferase E; E polypeptide, protein-glutamine-gamma-glutamyltransferase; TG(E); TGase E; TGase-3; transglutaminase E; 表皮转谷氨酰胺酶(TGM3); 谷氨酰胺转胺酶3;
背景信息:
Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium dependent. Transglutaminase 3 consists of two polypeptide chains activated from a single precursor protein by proteolysis. Transglutaminase 3 is involved the later stages of cell envelope formation in the epidermis and hair follicle.