基因名：
TBX5
产品别名：
HOS； TBX5； T-box transcription factor 5； T-box transcription factor 5； T-box transcription factor TBX5； T-box 5； T-box protein 5； T-框蛋白5(TBX5)； 转录因子Tbx5；
背景信息：
Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation.
Involvement in disease:Defects in TBX5 are the cause of Holt-Oram syndrome (HOS). HOS is a developmental disorder affecting the heart and upper limbs. It is characterized by thumb anomaly and atrial septal defects.
