基因名：
CNTN2
产品别名：
AXT； FAME5； TAG-1； TAX； TAX1； CNTN2； contactin 2； contactin 2； contactin-2； axonal glycoprotein TAG-1； axonin-1 cell adhesion molecule； contactin 2 (axonal)； contactin 2 (transiently expressed)； transient axonal glycoprotein 1； 接触蛋白2(CNTN2)； 瞬时表达轴索糖蛋白1；
背景信息：
Contactin-2 (CNTN2) is encoded by the CNTN2 gene,which belongs to the immunoglobulin superfamily and contactin family. It contains 4 fibronectin type-III domains and 6 Ig-like C2-type domains. It is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. CNTN2 may play a role in the formation of axon connections in the developing nervous system. In conjunction with another transmembrane protein, CNTNAP2, contributes to the organization of axonal domains at nodes of Ranvier by maintaining voltage-gated potassium channels at the juxtaparanodal region. It may also be involved in glial tumorigenesis and may provide a potential target for therapeutic intervention.
