重组ATP结合转运因子1蛋白

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重组ATP结合转运因子1蛋白

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重组抗原肽转运蛋白1(TAP1)
Recombinant TAP1

基因名：

TAP1

产品别名：

ABC17； ABCB2； APT1； D6S114E； PSF-1； PSF1； RING4； TAP1*0102N； TAP1N； TAP1； transporter 1, ATP binding cassette subfamily B member； transporter 1, ATP binding cassette subfamily B member； antigen peptide transporter 1； ABC transporter, MHC 1； ATP-binding cassette sub-family B member 2； ATP-binding cassette, sub-family B (MDR/TAP), member 2； peptide supply factor 1； peptide transporter PSF1； peptide transporter TAP1； peptide transporter involved in antigen processing 1； really interesting new gene 4 protein； transporter 1 ATP-binding cassette sub-family B； transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)； transporter associated with antigen processing； transporter, ATP-binding cassette, major histocompatibility complex, 1； ATP结合转运因子1；抗原肽转运蛋白1(TAP1)；

背景信息：

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is involved in the pumping of degraded cytosolic peptides across the endoplasmic reticulum into the membrane-bound compartment where class I molecules assemble. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease.