基因名：
ADAM17
产品别名：
ADAM18； CD156B； CSVP； NISBD； NISBD1； TACE； ADAM17； ADAM metallopeptidase domain 17； ADAM metallopeptidase domain 17； disintegrin and metalloproteinase domain-containing protein 17； ADAM metallopeptidase domain 18； TNF-alpha convertase； TNF-alpha convertase enzyme； TNF-alpha converting enzyme； a disintegrin and metalloproteinase 17； cartilage snake venom-like protease； snake venom-like protease； tumor necrosis factor, alpha, converting enzyme； 磷酸化CD156b； 肿瘤坏死因子α转换酶； 解整合素金属蛋白酶17(ADAM17)；
背景信息：
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway. [provided by RefSeq].
