基因名:
SRPK2
产品别名:
SFRSK2; SRPK2; SRSF protein kinase 2; SRSF protein kinase 2; SRSF protein kinase 2; SFRS protein kinase 2; SR protein kinase 2; SR-protein-specific kinase 2; serine kinase SRPK2; serine/arginine-rich protein-specific kinase 2; serine/arginine-rich splicing factor kinase 2; serine/threonine-protein kinase SRPK2; SRSF蛋白激酶2(SRPK2); 丝氨酸/苏氨酸蛋白激酶SRPK2;
背景信息:
SRPK2 belongs to the protein kinase superfamily. It phosphorylates RS domain-containing proteins, such as SFRS1 and SFRS2 on serine residues. It has a role in spliceosome assembly and in mediating the trafficking of splicing factors and appears to mediate HBV core protein phosphorylation which is a prerequisite for pregenomic RNA encapsidation into viral capsids. SRPK2 highly expressed in brain, moderately expressed in heart and skeletal muscle and at low levels in lung, liver, and kidney.