基因名：
SORD
产品别名：
HEL-S-95n； RDH； SDH； SORD1； SORDD； XDH； SORD； sorbitol dehydrogenase； sorbitol dehydrogenase； sorbitol dehydrogenase； (R,R)-butanediol dehydrogenase； L-iditol 2-dehydrogenase； epididymis secretory sperm binding protein Li 95n； polyol dehydrogenase； ribitol dehydrogenase； xylitol dehydrogenase； 山梨醇脱氢酶； 山梨醇脱氢酶(SDH)；
背景信息：
Sorbitol dehydrogenase, also known as L-iditol 2-dehydrogenase and SORD, is a member of the zinc-containing alcohol dehydrogenase family. SORD exsits in a homotetramer and binds one zinc ion per subunit. SORD is expressed in kidney and epithelial cells of both benign and malignant prostate tissue. SORD can converts sorbitol to fructose and catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase to make up the sorbitol pathway. SORD is up-regulated by androgens and down-regulated by castration. SORD may play a role in the sperm motility by providing an energetic source for sperm.
