基因名:
SLC5A5
产品别名:
NIS; TDH1; SLC5A5; solute carrier family 5 member 5; solute carrier family 5 member 5; sodium/iodide cotransporter; Na(+)/I(-) cotransporter; Na(+)/I(-) symporter; solute carrier family 5 (sodium iodide symporter), member 5; solute carrier family 5 (sodium/iodide cotransporter), member 5; 钠碘转运体蛋白; 钠碘运输蛋白(NIS);
背景信息:
catalyzes Na+/I- symporter activity plays a role in iodide transport and thyroid hormone generation.
Human Sodium Iodide Symporter (hNIS) is responsible for iodide concentrating ability within thyroid follicular cells. It is a membrane bound glycoprotein with 13 membrane spanning domains and 14 extramembranous domains. It may represent an autoantigen in thyroid.