基因名：
SH3BP2
产品别名：
3BP-2； 3BP2； CRBM； CRPM； RES4-23； SH3BP2； SH3 domain binding protein 2； SH3 domain binding protein 2； SH3 domain-binding protein 2； Abl-SH3 binding protein 2； TNFAIP3 interacting protein 2； epididymis secretory sperm binding protein； SH3域结合蛋白2(SH3BP2)； SH3结构域结合蛋白2； 磷酸化SH3结构域结合蛋白2；
背景信息：
The protein encoded by this gene has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases , and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
