基因名：
SGSH
产品别名：
HSS； MPS3A； SFMD； SGSH； N-sulfoglucosamine sulfohydrolase； N-sulfoglucosamine sulfohydrolase； N-sulphoglucosamine sulphohydrolase； heparan sulfate sulfatase； mucopolysaccharidosis type IIIA； sulfoglucosamine sulfamidase； sulphamidase； N-磺氨基葡糖磺基氢化酶(SGSH)； 磺氨基葡糖硫酸胺酶；
背景信息：
N-Sulphoglucosamine Sulphohydrolase (SGSH) is an important member of the sulfatase family which is involved in the degradation of heparin sulfate. SGSH binds one calcium ion per subunit as a cofactor. SGSH catalyzes N-sulfo-D-glucosamine and H2O to D-glucosamine and sulfate. SGSH deficiency is result in mucopolysaccharidosis type 3A (MPS3A), a recessive lysosomal storage disease characterized by neurological dysfunction but relatively mild somatic manifestations.
