基因名:
SECTM1
产品别名:
K12; SECTM; SECTM1; secreted and transmembrane 1; secreted and transmembrane 1; secreted and transmembrane protein 1; type 1a transmembrane protein; 分泌和跨膜蛋白1; 分泌跨膜蛋白1(SECTM1);
背景信息:
Secreted and Transmembrane Protein 1 (SECTM1) is a transmembrane and secreted protein that belongs to the SECTM family. SECTM1 is expressed in a perinuclear Golgi-like pattern. It is detected at the highest levels in peripheral blood leukocytes and breast cancer cell lines. SECTM1 is considered to participate in thymocyte signaling and the hematopoietic/immune system processes. It is reported that SECTM1 is a broadly expressed, IFN-γ-inducible molecule, which functions as a potent costimulatory ligand for T cell activation and is synergistic with anti-CD28.