基因名:
SATB1
产品别名:
DEFDA; KTZSL; SATB1; SATB homeobox 1; SATB homeobox 1; DNA-binding protein SATB1; special AT-rich sequence binding protein 1 (binds to nuclear matrix/scaffold-associating DNA); SATB同源框蛋白1(SATB1); 核基质结合区结合蛋白1; 磷酸化核基质结合区结合蛋白1;
背景信息:
SATB1 selectively binds double-stranded, special AT-rich RNA sequences in which 1 strand exclusively consists of well-mixed A, T, and C nucleotides (ATC sequences). It complexes mainly with p300 and this complex can bind to the gp91phox promoter and repress transcriptional activity. Its ability to repress transcription is regulated by nuclear matrix binding. It is expressed predominantly in the thymus.