基因名:
RNF6
产品别名:
RNF6; ring finger protein 6; ring finger protein 6; E3 ubiquitin-protein ligase RNF6; RING-H2 protein RNF-6; RING-type E3 ubiquitin transferase RNF6; ring finger protein (C3H2C3 type) 6; 环指蛋白6;
背景信息:
The protein encoded by this gene contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. Multiple alternatively spliced transcript variants encoding the same protein are observed. [provided by RefSeq, Jul 2008].