基因名：
RNF4
产品别名：
RES4-26； SLX5； SNURF； RNF4； ring finger protein 4； ring finger protein 4； E3 ubiquitin-protein ligase RNF4； E3 ubiquitin ligase RNF4； RING-type E3 ubiquitin transferase RNF4； small nuclear RING finger protein； 环指蛋白4(RNF4)；
背景信息：
RING-finger 4 (RNF4), also known as Snurf, is an E3 ubiquitin ligase. RNF4 is composed of four SUMO interaction motifs (SIMs) at the N-terminal and a RING domain at the C-terminal. The SIM domains prefer binding polySUMO chains; RNF4 functions to ubiquitinate polysumolyated proteins including promyelocytic leukaemia (PML), which target them for proteasomal degradation.
