基因名:
RELA
产品别名:
CMCU; NFKB3; p65; RELA; RELA proto-oncogene, NF-kB subunit; RELA proto-oncogene, NF-kB subunit; transcription factor p65; NF-kappa-B p65delta3; NF-kappa-B transcription factor p65; nuclear factor NF-kappa-B p65 subunit; nuclear factor of kappa light polypeptide gene enhancer in B-cells 3; v-rel avian reticuloendotheliosis viral oncogene homolog A; 乙酰化细胞核因子(K314/K315); 乙酰化细胞核因子NFKBp65; 核转录因子P65(NFKB3); 磷酸化细胞核因子; 磷酸化细胞核因子NF-κB p65; 磷酸化细胞核因子NFKBp65; 细胞核因子/k基因结合核因子; 细胞核因子NFKBp65;
背景信息:
NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011].