基因名:
KDM5A
产品别名:
RBBP-2; RBBP2; RBP2; KDM5A; lysine demethylase 5A; lysine demethylase 5A; lysine-specific demethylase 5A; Jumonji, AT rich interactive domain 1A (RBP2-like); [histone H3]-trimethyl-L-lysine(4) demethylase 5A; histone demethylase JARID1A; jumonji/ARID domain-containing protein 1A; lysine (K)-specific demethylase 5A; retinoblastoma binding protein 2; 组蛋白去甲基化酶JARID1A;
背景信息:
This gene encodes a member of the Jumonji, AT-rich interactive domain 1 (JARID1) histone demethylase protein family. The encoded protein plays a role in gene regulation through the histone code by specifically demethylating lysine 4 of histone H3. The encoded protein interacts with many other proteins, including retinoblastoma protein, and is implicated in the transcriptional regulation of Hox genes and cytokines. This gene may play a role in tumor progression. [provided by RefSeq, Aug 2013]