基因名:
PTPN14
产品别名:
CATLPH; PEZ; PTP36; PTPD2; PTPN14; protein tyrosine phosphatase non-receptor type 14; protein tyrosine phosphatase non-receptor type 14; tyrosine-protein phosphatase non-receptor type 14; cytoskeletal-associated protein tyrosine phosphatase; protein-tyrosine phosphatase pez; 细胞骨架相关蛋白酪氨酸磷酸酶2; 非受体型蛋白酪氨酸磷酸酶14(PTPN14);
背景信息:
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal noncatalytic domain similar to that of band 4.1 superfamily cytoskeleton-associated proteins, which suggested the membrane or cytoskeleton localization of this protein. It appears to regulate lymphatic development in mammals, and a loss of function mutation has been found in a kindred with a lymphedema-choanal atresia. [provided by RefSeq, Sep 2010]