基因名：
PTPN7
产品别名：
BPTP-4； HEPTP； LC-PTP； LPTP； PTPNI； PTPN7； protein tyrosine phosphatase non-receptor type 7； protein tyrosine phosphatase non-receptor type 7； tyrosine-protein phosphatase non-receptor type 7； dual specificity phosphatase 1； hematopoietic protein-tyrosine phosphatase； protein-tyrosine phosphatase LC-PTP； protein-tyrosine phosphatase, nonreceptor-type, stress induced； 磷酸化非受体型蛋白酪氨酸磷酸酶7； 非受体型蛋白酪氨酸磷酸酶7；
背景信息：
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The non-catalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP was shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq].
