基因名：
PTGS2
产品别名：
COX-2； COX2； GRIPGHS； PGG/HS； PGHS-2； PHS-2； hCox-2； PTGS2； prostaglandin-endoperoxide synthase 2； prostaglandin-endoperoxide synthase 2； prostaglandin G/H synthase 2； PGH synthase 2； PHS II； cyclooxygenase 2； cyclooxygenase 2b； prostaglandin H2 synthase 2； prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)； 环氧合酶2/前列腺素内过氧化物合成酶2； 环氧合酶2/前列腺素内过氧化物合成酶2蛋白；
背景信息：
Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis. [provided by RefSeq, Feb 2009]
